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portfolio
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publications
WikiPathways: building research communities on biological pathways
Published in Nucleic Acids Research, 2012
Recommended citation: T. Kelder, M. P. van Iersel, K. Hanspers, M. Kutmon, B. R. Conklin, C. T. Evelo, A. R. Pico. (2012). "WikiPathways: building research communities on biological pathways." Nucleic Acids Research.
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A pathway approach to investigate the function and regulation of SREBPs
Published in Genes & Nutrition, 2013
Recommended citation: S. Daemen, M. Kutmon, C. T. Evelo. (2013). "A pathway approach to investigate the function and regulation of SREBPs." Genes & Nutrition.
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CyTargetLinker: A Cytoscape App to Integrate Regulatory Interactions in Network Analysis
Published in PLoS ONE, 2013
Recommended citation: M. Kutmon, T. Kelder, P. Mandaviya, C. T. A. Evelo, S. L. Coort. (2013). "CyTargetLinker: A Cytoscape App to Integrate Regulatory Interactions in Network Analysis." PLoS ONE.
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A network biology workflow to study transcriptomics data of the diabetic liver
Published in BMC Genomics, 2014
Recommended citation: M. Kutmon, C. T. Evelo, S. L. Coort. (2014). "A network biology workflow to study transcriptomics data of the diabetic liver." BMC Genomics.
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WikiPathways App for Cytoscape: Making biological pathways amenable to network analysis and visualization
Published in F1000Research, 2014
Recommended citation: M. Kutmon, S. Lotia, C. T. Evelo, A. R. Pico. (2014). "WikiPathways App for Cytoscape: Making biological pathways amenable to network analysis and visualization." F1000Research.
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Integrative network-based analysis of mRNA and microRNA expression in 1,25-dihydroxyvitamin D3-treated cancer cells
Published in Genes & Nutrition, 2015
Recommended citation: M. Kutmon, S. L. Coort, K. de Nooijer, C. Lemmens, C. T. Evelo. (2015). "Integrative network-based analysis of mRNA and microRNA expression in 1,25-dihydroxyvitamin D3-treated cancer cells." Genes & Nutrition.
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Automatically visualise and analyse data on pathways using PathVisioRPC from any programming environment
Published in BMC Bioinformatics, 2015
Recommended citation: A. Bohler, L. M. T. Eijssen, M. P. van Iersel, C. Leemans, E. L. Willighagen, M. Kutmon, M. Jaillard, C. T. Evelo. (2015). "Automatically visualise and analyse data on pathways using PathVisioRPC from any programming environment." BMC Bioinformatics.
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PathVisio 3: An Extendable Pathway Analysis Toolbox
Published in PLOS Computational Biology, 2015
Recommended citation: M. Kutmon, M. P. van Iersel, A. Bohler, T. Kelder, N. Nunes, A. R. Pico, C. T. Evelo. (2015). "PathVisio 3: An Extendable Pathway Analysis Toolbox." PLOS Computational Biology.
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Inferring causal molecular networks: empirical assessment through a community-based effort
Published in Nature Methods, 2016
Recommended citation: , S. M. Hill, L. M. Heiser, T. Cokelaer, M. Unger, N. K. Nesser, D. E. Carlin, Y. Zhang, A. Sokolov, E. O. Paull, C. K. Wong, K. Graim, A. Bivol, H. Wang, F. Zhu, B. Afsari, L. V. Danilova, A. V. Favorov, W. S. Lee, D. Taylor, C. W. Hu, B. L. Long, D. P. Noren, A. J. Bisberg, G. B. Mills, J. W. Gray, M. Kellen, T. Norman, S. Friend, A. A. Qutub, E. J. Fertig, Y. Guan, M. Song, J. M. Stuart, P. T. Spellman, H. Koeppl, G. Stolovitzky, J. Saez-Rodriguez, S. Mukherjee. (2016). "Inferring causal molecular networks: empirical assessment through a community-based effort." Nature Methods.
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WikiPathways: capturing the full diversity of pathway knowledge
Published in Nucleic Acids Research, 2016
Recommended citation: M. Kutmon, A. Riutta, N. Nunes, K. Hanspers, E. L. Willighagen, A. Bohler, J. Mélius, A. Waagmeester, S. R. Sinha, R. Miller, S. L. Coort, E. Cirillo, B. Smeets, C. T. Evelo, A. R. Pico. (2016). "WikiPathways: capturing the full diversity of pathway knowledge." Nucleic Acids Research.
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The systems biology format converter
Published in BMC Bioinformatics, 2016
Recommended citation: N. Rodriguez, J. Pettit, P. Dalle Pezze, L. Li, A. Henry, M. P. van Iersel, G. Jalowicki, M. Kutmon, K. N. Natarajan, D. Tolnay, M. I. Stefan, C. T. Evelo, N. Le Novère. (2016). "The systems biology format converter." BMC Bioinformatics.
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Reactome from a WikiPathways Perspective
Published in PLOS Computational Biology, 2016
Recommended citation: A. Bohler, G. Wu, M. Kutmon, L. A. Pradhana, S. L. Coort, K. Hanspers, R. Haw, A. R. Pico, C. T. Evelo. (2016). "Reactome from a WikiPathways Perspective." PLOS Computational Biology.
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Using the Semantic Web for Rapid Integration of WikiPathways with Other Biological Online Data Resources
Published in PLOS Computational Biology, 2016
Recommended citation: A. Waagmeester, M. Kutmon, A. Riutta, R. Miller, E. L. Willighagen, C. T. Evelo, A. R. Pico. (2016). "Using the Semantic Web for Rapid Integration of WikiPathways with Other Biological Online Data Resources." PLOS Computational Biology.
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Visualizing the regulatory role of Angiopoietin-like protein 8 (ANGPTL8) in glucose and lipid metabolic pathways
Published in Genomics, 2017
Recommended citation: A. Siddiqa, E. Cirillo, S. H. Tareen, A. Ali, M. Kutmon, L. M. Eijssen, J. Ahmad, C. T. Evelo, S. L. Coort. (2017). "Visualizing the regulatory role of Angiopoietin-like protein 8 (ANGPTL8) in glucose and lipid metabolic pathways." Genomics.
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Sexual Dimorphism, Age, and Fat Mass Are Key Phenotypic Drivers of Proteomic Signatures
Published in Journal of Proteome Research, 2017
Recommended citation: A. M. Curran, C. Fogarty Draper, M. Scott-Boyer, A. Valsesia, H. M. Roche, M. F. Ryan, M. J. Gibney, M. Kutmon, C. T. Evelo, S. L. Coort, A. Astrup, W. H. Saris, L. Brennan, J. Kaput. (2017). "Sexual Dimorphism, Age, and Fat Mass Are Key Phenotypic Drivers of Proteomic Signatures." Journal of Proteome Research.
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WikiPathways: a multifaceted pathway database bridging metabolomics to other omics research
Published in Nucleic Acids Research, 2018
Recommended citation: D. N. Slenter, M. Kutmon, K. Hanspers, A. Riutta, J. Windsor, N. Nunes, J. Mélius, E. Cirillo, S. L. Coort, D. Digles, F. Ehrhart, P. Giesbertz, M. Kalafati, M. Martens, R. Miller, K. Nishida, L. Rieswijk, A. Waagmeester, L. M. T. Eijssen, C. T. Evelo, A. R. Pico, E. L. Willighagen. (2018). "WikiPathways: a multifaceted pathway database bridging metabolomics to other omics research." Nucleic Acids Research.
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Exploring the cellular network of metabolic flexibility in the adipose tissue
Published in Genes & Nutrition, 2018
Recommended citation: S. H. K. Tareen, M. Kutmon, M. E. Adriaens, E. C. M. Mariman, T. M. de Kok, I. C. W. Arts, C. T. Evelo. (2018). "Exploring the cellular network of metabolic flexibility in the adipose tissue." Genes & Nutrition.
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Explicit interaction information from WikiPathways in RDF facilitates drug discovery in the Open PHACTS Discovery Platform
Published in F1000Research, 2018
Recommended citation: R. A. Miller, P. Woollard, E. L. Willighagen, D. Digles, M. Kutmon, A. Loizou, A. Waagmeester, S. Senger, C. T. Evelo. (2018). "Explicit interaction information from WikiPathways in RDF facilitates drug discovery in the Open PHACTS Discovery Platform." F1000Research.
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Providing gene-to-variant and variant-to-gene database identifier mappings to use with BridgeDb mapping services.
Published in F1000Research, 2018
Recommended citation: F. Ehrhart, J. Melius, E. Cirillo, M. Kutmon, E. L. Willighagen, S. L. Coort, L. M. Curfs, C. T. Evelo. (2018). "Providing gene-to-variant and variant-to-gene database identifier mappings to use with BridgeDb mapping services.." F1000Research.
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From SNPs to pathways: Biological interpretation of type 2 diabetes (T2DM) genome wide association study (GWAS) results
Published in PLOS ONE, 2018
Recommended citation: E. Cirillo, M. Kutmon, M. Gonzalez Hernandez, T. Hooimeijer, M. E. Adriaens, L. M. T. Eijssen, L. D. Parnell, S. L. Coort, C. T. Evelo. (2018). "From SNPs to pathways: Biological interpretation of type 2 diabetes (T2DM) genome wide association study (GWAS) results." PLOS ONE.
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Pathway analysis of transcriptomic data shows immunometabolic effects of vitamin D
Published in Journal of Molecular Endocrinology, 2018
Recommended citation: A. Muñoz Garcia, M. Kutmon, L. Eijssen, M. Hewison, C. T. Evelo, S. L. Coort. (2018). "Pathway analysis of transcriptomic data shows immunometabolic effects of vitamin D." Journal of Molecular Endocrinology.
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Biological Pathways Leading From ANGPTL8 to Diabetes Mellitus–A Co-expression Network Based Analysis
Published in Frontiers in Physiology, 2018
Recommended citation: A. Siddiqa, E. Cirillo, S. H. K. Tareen, A. Ali, M. Kutmon, L. M. T. Eijssen, J. Ahmad, C. T. Evelo, S. L. Coort. (2018). "Biological Pathways Leading From ANGPTL8 to Diabetes Mellitus–A Co-expression Network Based Analysis." Frontiers in Physiology.
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Profiling Cellular Processes in Adipose Tissue during Weight Loss Using Time Series Gene Expression
Published in Genes, 2018
Recommended citation: S. H. K. Tareen, M. E. Adriaens, I. C. W. Arts, T. M. De Kok, R. G. Vink, N. J. T. Roumans, M. A. Van Baak, E. C. M. Mariman, C. T. Evelo, M. Kutmon. (2018). "Profiling Cellular Processes in Adipose Tissue during Weight Loss Using Time Series Gene Expression." Genes.
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A bioinformatics workflow to decipher transcriptomic data from vitamin D studies
Published in The Journal of Steroid Biochemistry and Molecular Biology, 2019
Recommended citation: A. Muñoz García, L. M. Eijssen, M. Kutmon, C. Sarathy, A. Cengo, M. Hewison, C. T. Evelo, M. Lenz, S. L. Coort. (2019). "A bioinformatics workflow to decipher transcriptomic data from vitamin D studies." The Journal of Steroid Biochemistry and Molecular Biology.
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Logical modelling reveals the PDC-PDK interaction as the regulatory switch driving metabolic flexibility at the cellular level
Published in Genes & Nutrition, 2019
Recommended citation: S. H. Tareen, M. Kutmon, I. C. Arts, T. M. de Kok, C. T. Evelo, M. E. Adriaens. (2019). "Logical modelling reveals the PDC-PDK interaction as the regulatory switch driving metabolic flexibility at the cellular level." Genes & Nutrition.
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CyTargetLinker app update: A flexible solution for network extension in Cytoscape
Published in F1000Research, 2019
Recommended citation: M. Kutmon, F. Ehrhart, E. L. Willighagen, C. T. Evelo, S. L. Coort. (2019). "CyTargetLinker app update: A flexible solution for network extension in Cytoscape." F1000Research.
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Beyond Pathway Analysis: Identification of Active Subnetworks in Rett Syndrome
Published in Frontiers in Genetics, 2019
Recommended citation: R. A. Miller, F. Ehrhart, L. M. T. Eijssen, D. N. Slenter, L. M. G. Curfs, C. T. Evelo, E. L. Willighagen, M. Kutmon. (2019). "Beyond Pathway Analysis: Identification of Active Subnetworks in Rett Syndrome." Frontiers in Genetics.
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Stratifying cellular metabolism during weight loss: an interplay of metabolism, metabolic flexibility and inflammation
Published in Scientific Reports, 2020
Recommended citation: S. H. K. Tareen, M. Kutmon, T. M. de Kok, E. C. M. Mariman, M. A. van Baak, C. T. Evelo, M. E. Adriaens, I. C. W. Arts. (2020). "Stratifying cellular metabolism during weight loss: an interplay of metabolism, metabolic flexibility and inflammation." Scientific Reports.
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Comprehensive bioinformatics analysis of trabecular meshwork gene expression data to unravel the molecular pathogenesis of primary open‐angle glaucoma
Published in Acta Ophthalmologica, 2020
Recommended citation: I. Liesenborghs, L. M. T. Eijssen, M. Kutmon, T. G. M. F. Gorgels, C. T. Evelo, H. J. M. Beckers, C. A. B. Webers, J. S. A. G. Schouten. (2020). "Comprehensive bioinformatics analysis of trabecular meshwork gene expression data to unravel the molecular pathogenesis of primary open‐angle glaucoma." Acta Ophthalmologica.
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The Molecular Processes in the Trabecular Meshwork After Exposure to Corticosteroids and in Corticosteroid-Induced Ocular Hypertension
Published in Investigative Opthalmology & Visual Science, 2020
Recommended citation: I. Liesenborghs, L. M. T. Eijssen, M. Kutmon, T. G. M. F. Gorgels, C. T. Evelo, H. J. M. Beckers, C. A. B. Webers, J. S. A. G. Schouten. (2020). "The Molecular Processes in the Trabecular Meshwork After Exposure to Corticosteroids and in Corticosteroid-Induced Ocular Hypertension." Investigative Opthalmology & Visual Science.
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Pathway information extracted from 25 years of pathway figures
Published in Genome Biology, 2020
Recommended citation: K. Hanspers, A. Riutta, M. Summer-Kutmon, A. R. Pico. (2020). "Pathway information extracted from 25 years of pathway figures." Genome Biology.
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SBML Level 3: an extensible format for the exchange and reuse of biological models
Published in Molecular Systems Biology, 2020
Recommended citation: S. M. Keating, D. Waltemath, M. König, F. Zhang, A. Dräger, C. Chaouiya, F. T. Bergmann, A. Finney, C. S. Gillespie, T. Helikar, S. Hoops, R. S. Malik‐Sheriff, S. L. Moodie, I. I. Moraru, C. J. Myers, A. Naldi, B. G. Olivier, S. Sahle, J. C. Schaff, L. P. Smith, M. J. Swat, D. Thieffry, L. Watanabe, D. J. Wilkinson, M. L. Blinov, K. Begley, J. R. Faeder, H. F. Gómez, T. M. Hamm, Y. Inagaki, W. Liebermeister, A. L. Lister, D. Lucio, E. Mjolsness, C. J. Proctor, K. Raman, N. Rodriguez, C. A. Shaffer, B. E. Shapiro, J. Stelling, N. Swainston, N. Tanimura, J. Wagner, M. Meier‐Schellersheim, H. M. Sauro, B. Palsson, H. Bolouri, H. Kitano, A. Funahashi, H. Hermjakob, J. C. Doyle, M. Hucka, , R. R. Adams, N. A. Allen, B. R. Angermann, M. Antoniotti, G. D. Bader, J. Červený, M. Courtot, C. D. Cox, P. Dalle Pezze, E. Demir, W. S. Denney, H. Dharuri, J. Dorier, D. Drasdo, A. Ebrahim, J. Eichner, J. Elf, L. Endler, C. T. Evelo, C. Flamm, R. M. Fleming, M. Fröhlich, M. Glont, E. Gonçalves, M. Golebiewski, H. Grabski, A. Gutteridge, D. Hachmeister, L. A. Harris, B. D. Heavner, R. Henkel, W. S. Hlavacek, B. Hu, D. R. Hyduke, H. de Jong, N. Juty, P. D. Karp, J. R. Karr, D. B. Kell, R. Keller, I. Kiselev, S. Klamt, E. Klipp, C. Knüpfer, F. Kolpakov, F. Krause, M. Kutmon, C. Laibe, C. Lawless, L. Li, L. M. Loew, R. Machne, Y. Matsuoka, P. Mendes, H. Mi, F. Mittag, P. T. Monteiro, K. N. Natarajan, P. M. Nielsen, T. Nguyen, A. Palmisano, J. Pettit, T. Pfau, R. D. Phair, T. Radivoyevitch, J. M. Rohwer, O. A. Ruebenacker, J. Saez‐Rodriguez, M. Scharm, H. Schmidt, F. Schreiber, M. Schubert, R. Schulte, S. C. Sealfon, K. Smallbone, S. Soliman, M. I. Stefan, D. P. Sullivan, K. Takahashi, B. Teusink, D. Tolnay, I. Vazirabad, A. von Kamp, U. Wittig, C. Wrzodek, F. Wrzodek, I. Xenarios, A. Zhukova, J. Zucker. (2020). "
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Identification of Biological Pathways Contributing to Marbling in Skeletal Muscle to Improve Beef Cattle Breeding
Published in Frontiers in Genetics, 2020
Recommended citation: Z. Roudbari, S. L. Coort, M. Kutmon, L. Eijssen, J. Melius, T. Sadkowski, C. T. Evelo. (2020). "Identification of Biological Pathways Contributing to Marbling in Skeletal Muscle to Improve Beef Cattle Breeding." Frontiers in Genetics.
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EFMviz: A COBRA Toolbox Extension to Visualize Elementary Flux Modes in Genome-Scale Metabolic Models
Published in Metabolites, 2020
Recommended citation: C. Sarathy, M. Kutmon, M. Lenz, M. E. Adriaens, C. T. Evelo, I. C. Arts. (2020). "EFMviz: A COBRA Toolbox Extension to Visualize Elementary Flux Modes in Genome-Scale Metabolic Models." Metabolites.
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Integrative multiomics analysis of human atherosclerosis reveals a serum response factor‐driven network associated with intraplaque hemorrhage
Published in Clinical and Translational Medicine, 2021
Recommended citation: H. Jin, P. Goossens, P. Juhasz, W. Eijgelaar, M. Manca, J. M. H. Karel, E. Smirnov, C. J. J. M. Sikkink, B. M. E. Mees, O. Waring, K. van Kuijk, G. E. Fazzi, M. J. J. Gijbels, M. Kutmon, C. T. A. Evelo, U. Hedin, M. J. A. P. Daemen, J. C. Sluimer, L. Matic, E. A. L. Biessen. (2021). "Integrative multiomics analysis of human atherosclerosis reveals a serum response factor‐driven network associated with intraplaque hemorrhage." Clinical and Translational Medicine.
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A resource to explore the discovery of rare diseases and their causative genes
Published in Scientific Data, 2021
Recommended citation: F. Ehrhart, E. L. Willighagen, M. Kutmon, M. van Hoften, L. M. G. Curfs, C. T. Evelo. (2021). "A resource to explore the discovery of rare diseases and their causative genes." Scientific Data.
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WikiPathways: connecting communities
Published in Nucleic Acids Research, 2021
Recommended citation: M. Martens, A. Ammar, A. Riutta, A. Waagmeester, D. N. Slenter, K. Hanspers, R. A. Miller, D. Digles, E. N. Lopes, F. Ehrhart, L. J. Dupuis, L. A. Winckers, S. L. Coort, E. L. Willighagen, C. T. Evelo, A. R. Pico, M. Kutmon. (2021). "WikiPathways: connecting communities." Nucleic Acids Research.
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An interferon-related signature characterizes the whole blood transcriptome profile of insulin-resistant individuals—the CODAM study
Published in Genes & Nutrition, 2021
Recommended citation: M. Kalafati, M. Kutmon, C. T. Evelo, C. J. H. van der Kallen, C. G. Schalkwijk, C. D. A. Stehouwer, B. I. O. S. Consortium, E. E. Blaak, M. M. J. van Greevenbroek, M. Adriaens. (2021). "An interferon-related signature characterizes the whole blood transcriptome profile of insulin-resistant individuals—the CODAM study." Genes & Nutrition.
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A protocol for adding knowledge to Wikidata: aligning resources on human coronaviruses
Published in BMC Biology, 2021
Recommended citation: A. Waagmeester, E. L. Willighagen, A. I. Su, M. Kutmon, J. E. L. Gayo, D. Fernández-Álvarez, Q. Groom, P. J. Schaap, L. M. Verhagen, J. J. Koehorst. (2021). "A protocol for adding knowledge to Wikidata: aligning resources on human coronaviruses." BMC Biology.
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Ten simple rules for creating reusable pathway models for computational analysis and visualization
Published in PLOS Computational Biology, 2021
Recommended citation: K. Hanspers, M. Kutmon, S. L. Coort, D. Digles, L. J. Dupuis, F. Ehrhart, F. Hu, E. N. Lopes, M. Martens, N. Pham, W. Shin, D. N. Slenter, A. Waagmeester, E. L. Willighagen, L. A. Winckers, C. T. Evelo, A. R. Pico. (2021). "Ten simple rules for creating reusable pathway models for computational analysis and visualization." PLOS Computational Biology.
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Comparison of metabolic states using genome-scale metabolic models
Published in PLOS Computational Biology, 2021
Recommended citation: C. Sarathy, M. Breuer, M. Kutmon, M. E. Adriaens, C. T. Evelo, I. C. W. Arts. (2021). "Comparison of metabolic states using genome-scale metabolic models." PLOS Computational Biology.
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Assessing the Contribution of Relative Macrophage Frequencies to Subcutaneous Adipose Tissue
Published in Frontiers in Nutrition, 2021
Recommended citation: M. Kalafati, M. Lenz, G. Ertaylan, I. C. W. Arts, C. T. Evelo, M. M. J. van Greevenbroek, E. E. Blaak, M. Adriaens, M. Kutmon. (2021). "Assessing the Contribution of Relative Macrophage Frequencies to Subcutaneous Adipose Tissue." Frontiers in Nutrition.
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Investigating the Molecular Processes behind the Cell-Specific Toxicity Response to Titanium Dioxide Nanobelts
Published in International Journal of Molecular Sciences, 2021
Recommended citation: L. A. Winckers, C. T. Evelo, E. L. Willighagen, M. Kutmon. (2021). "Investigating the Molecular Processes behind the Cell-Specific Toxicity Response to Titanium Dioxide Nanobelts." International Journal of Molecular Sciences.
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Research Techniques Made Simple: Lipidomic Analysis in Skin Research
Published in Journal of Investigative Dermatology, 2022
Recommended citation: M. Sochorová, K. Vávrová, M. Fedorova, Z. Ni, D. Slenter, M. Kutmon, E. L. Willighagen, S. Letsiou, D. Töröcsik, M. Marchetti-Deschmann, S. Zoratto, C. Kremslehner, F. Gruber. (2022). "Research Techniques Made Simple: Lipidomic Analysis in Skin Research." Journal of Investigative Dermatology.
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Finding the “switch” in platelet activation: prediction of key mediators involved in reversal of platelet activation using a novel network biology approach
Published in Journal of Proteomics, 2022
Recommended citation: T. Lemmens, D. Coenen, F. Swieringa, I. Niessen, S. Coort, R. Koenen, M. Kutmon, J. Cosemans. (2022). "Finding the “switch” in platelet activation: prediction of key mediators involved in reversal of platelet activation using a novel network biology approach." Journal of Proteomics.
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A systematically derived overview of the non-ubiquitous pathways and genes that define the molecular and genetic signature of the healthy trabecular meshwork
Published in Genomics, 2022
Recommended citation: I. Liesenborghs, J. S. Schouten, M. Kutmon, T. G. Gorgels, C. T. Evelo, W. H. Hubens, H. J. Beckers, C. A. Webers, L. M. Eijssen. (2022). "A systematically derived overview of the non-ubiquitous pathways and genes that define the molecular and genetic signature of the healthy trabecular meshwork." Genomics.
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Systems Biology in ELIXIR: modelling in the spotlight
Published in F1000Research, 2022
Recommended citation: V. Martins dos Santos, M. Anton, B. Szomolay, M. Ostaszewski, I. Arts, R. Benfeitas, V. Dominguez Del Angel, P. Ferk, D. Fey, C. Goble, M. Golebiewski, K. Gruden, K. F. Heil, H. Hermjakob, P. Kahlem, M. I. Klapa, J. Koehorst, A. Kolodkin, M. Kutmon, B. Leskošek, S. Moretti, W. Müller, M. Pagni, T. Rezen, M. Rocha, D. Rozman, D. Šafránek, R. S. M. Sheriff, M. Suarez Diez, K. Van Steen, H. V. Westerhoff, U. Wittig, K. Wolstencroft, A. Zupanic, C. T. Evelo, J. M. Hancock. (2022). "Systems Biology in ELIXIR: modelling in the spotlight." F1000Research.
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Understanding signaling and metabolic paths using semantified and harmonized information about biological interactions
Published in PLOS ONE, 2022
Recommended citation: R. A. Miller, M. Kutmon, A. Bohler, A. Waagmeester, C. T. Evelo, E. L. Willighagen. (2022). "Understanding signaling and metabolic paths using semantified and harmonized information about biological interactions." PLOS ONE.
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Tissue-specific pathway activities: A retrospective analysis in COVID-19 patients
Published in Frontiers in Immunology, 2022
Recommended citation: N. Pham, F. Hu, C. T. Evelo, M. Kutmon. (2022). "Tissue-specific pathway activities: A retrospective analysis in COVID-19 patients." Frontiers in Immunology.
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Elucidating the Corneal Endothelial Cell Proliferation Capacity through an Interspecies Transcriptome Comparison
Published in Advanced Biology, 2023
Recommended citation: P. Català, F. Vivensang, D. van Beek, M. E. Adriaens, M. M. Dickman, V. L. LaPointe, M. Kutmon. (2023). "Elucidating the Corneal Endothelial Cell Proliferation Capacity through an Interspecies Transcriptome Comparison." Advanced Biology.
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Guiding the choice of informatics software and tools for lipidomics research applications
Published in Nature Methods, 2023
Recommended citation: Z. Ni, M. Wölk, G. Jukes, K. Mendivelso Espinosa, R. Ahrends, L. Aimo, J. Alvarez-Jarreta, S. Andrews, R. Andrews, A. Bridge, G. C. Clair, M. J. Conroy, E. Fahy, C. Gaud, L. Goracci, J. Hartler, N. Hoffmann, D. Kopczyinki, A. Korf, A. F. Lopez-Clavijo, A. Malik, J. M. Ackerman, M. R. Molenaar, C. O’Donovan, T. Pluskal, A. Shevchenko, D. Slenter, G. Siuzdak, M. Kutmon, H. Tsugawa, E. L. Willighagen, J. Xia, V. B. O’Donnell, M. Fedorova. (2023). "Guiding the choice of informatics software and tools for lipidomics research applications." Nature Methods.
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Allele-specific expression analysis for complex genetic phenotypes applied to a unique dilated cardiomyopathy cohort
Published in Scientific Reports, 2023
Recommended citation: D. van Beek, J. Verdonschot, K. Derks, H. Brunner, T. M. de Kok, I. C. W. Arts, S. Heymans, M. Kutmon, M. Adriaens. (2023). "Allele-specific expression analysis for complex genetic phenotypes applied to a unique dilated cardiomyopathy cohort." Scientific Reports.
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Human Monocytes Exposed to SARS-CoV-2 Display Features of Innate Immune Memory Producing High Levels of CXCL10 upon Restimulation
Published in Journal of Innate Immunity, 2023
Recommended citation: J. Cvetkovic, R. H. Jacobi, A. Miranda-Bedate, N. Pham, M. Kutmon, J. Groot, M. D. van de Garde, E. Pinelli. (2023). "Human Monocytes Exposed to SARS-CoV-2 Display Features of Innate Immune Memory Producing High Levels of CXCL10 upon Restimulation." Journal of Innate Immunity.
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Author Correction: A protocol for adding knowledge to Wikidata: aligning resources on human coronaviruses
Published in BMC Biology, 2023
Recommended citation: A. Waagmeester, E. L. Willighagen, A. I. Su, M. Kutmon, J. E. L. Gayo, D. Fernández-Álvarez, Q. Groom, P. J. Schaap, L. M. Verhagen, J. J. Koehorst. (2023). "Author Correction: A protocol for adding knowledge to Wikidata: aligning resources on human coronaviruses." BMC Biology.
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Exploring pathway interactions to detect molecular mechanisms of disease: 22q11.2 deletion syndrome
Published in Orphanet Journal of Rare Diseases, 2023
Recommended citation: W. Shin, M. Kutmon, E. Mina, T. van Amelsvoort, C. T. Evelo, F. Ehrhart. (2023). "Exploring pathway interactions to detect molecular mechanisms of disease: 22q11.2 deletion syndrome." Orphanet Journal of Rare Diseases.
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A novel insight into neurological disorders through HDAC6 protein–protein interactions
Published in Scientific Reports, 2024
Recommended citation: N. Bahram Sangani, J. Koetsier, J. Mélius, M. Kutmon, F. Ehrhart, C. T. Evelo, L. M. G. Curfs, C. P. Reutelingsperger, L. M. T. Eijssen. (2024). "A novel insight into neurological disorders through HDAC6 protein–protein interactions." Scientific Reports.
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WikiPathways 2024: next generation pathway database
Published in Nucleic Acids Research, 2024
Recommended citation: A. Agrawal, H. Balcı, K. Hanspers, S. L. Coort, M. Martens, D. N. Slenter, F. Ehrhart, D. Digles, A. Waagmeester, I. Wassink, T. Abbassi-Daloii, E. N. Lopes, A. Iyer, J. M. Acosta, L. G. Willighagen, K. Nishida, A. Riutta, H. Basaric, C. T. Evelo, E. L. Willighagen, M. Kutmon, A. R. Pico. (2024). "WikiPathways 2024: next generation pathway database." Nucleic Acids Research.
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Systems Biology in ELIXIR: modelling in the spotlight
Published in F1000Research, 2024
Recommended citation: V. Martins dos Santos, M. Anton, B. Szomolay, M. Ostaszewski, I. Arts, R. Benfeitas, V. Dominguez Del Angel, E. Domínguez-Romero, P. Ferk, D. Fey, C. Goble, M. Golebiewski, K. Gruden, K. F. Heil, H. Hermjakob, P. Kahlem, M. I. Klapa, J. Koehorst, A. Kolodkin, M. Kutmon, B. Leskošek, S. Moretti, W. Müller, M. Pagni, T. Rezen, M. Rocha, D. Rozman, D. Šafránek, W. T. Scott, R. S. M. Sheriff, M. Suarez Diez, K. Van Steen, H. V. Westerhoff, U. Wittig, K. Wolstencroft, A. Zupanic, C. T. Evelo, J. M. Hancock. (2024). "Systems Biology in ELIXIR: modelling in the spotlight." F1000Research.
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Drug-target identification in COVID-19 disease mechanisms using computational systems biology approaches
Published in Frontiers in Immunology, 2024
Recommended citation: A. Niarakis, M. Ostaszewski, A. Mazein, I. Kuperstein, M. Kutmon, M. E. Gillespie, A. Funahashi, M. L. Acencio, A. Hemedan, M. Aichem, K. Klein, T. Czauderna, F. Burtscher, T. G. Yamada, Y. Hiki, N. F. Hiroi, F. Hu, N. Pham, F. Ehrhart, E. L. Willighagen, A. Valdeolivas, A. Dugourd, F. Messina, M. Esteban-Medina, M. Peña-Chilet, K. Rian, S. Soliman, S. S. Aghamiri, B. L. Puniya, A. Naldi, T. Helikar, V. Singh, M. F. Fernández, V. Bermudez, E. Tsirvouli, A. Montagud, V. Noël, M. Ponce-de-Leon, D. Maier, A. Bauch, B. M. Gyori, J. A. Bachman, A. Luna, J. Piñero, L. I. Furlong, I. Balaur, A. Rougny, Y. Jarosz, R. W. Overall, R. Phair, L. Perfetto, L. Matthews, D. A. B. Rex, M. Orlic-Milacic, L. C. M. Gomez, B. De Meulder, J. M. Ravel, B. Jassal, V. Satagopam, G. Wu, M. Golebiewski, P. Gawron, L. Calzone, J. S. Beckmann, C. T. Evelo, P. D’Eustachio, F. Schreiber, J. Saez-Rodriguez, J. Dopazo, M. Kuiper, A. Valencia, O. Wolkenhauer, H. Kitano, E. Barillot, C. Auffray, R. Balling, R. Schneider, . (2024). "Drug-target identification in COVID-19 disease mechanisms using computational systems biology approaches." Frontiers in Immunology.
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The unusual suspect: A novel role for intermediate filament proteins in mitochondrial morphology
Published in Mitochondrion, 2025
Recommended citation: I. M. Hemel, C. Steen, S. L. Denil, G. Ertaylan, M. Kutmon, M. Adriaens, M. Gerards. (2025). "The unusual suspect: A novel role for intermediate filament proteins in mitochondrial morphology." Mitochondrion.
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A versatile and interoperable computational framework for the analysis and modeling of COVID-19 disease mechanisms
Published in , 2025
Recommended citation: A. Niarakis, M. Ostaszewski, A. Mazein, I. Kuperstein, M. Kutmon, M. E. Gillespie, A. Funahashi, M. L. Acencio, A. Hemedan, M. Aichem, K. Klein, T. Czauderna, F. Burtscher, T. G. Yamada, Y. Hiki, N. F. Hiroi, F. Hu, N. Pham, F. Ehrhart, E. L. Willighagen, A. Valdeolivas, A. Dugourd, F. Messina, M. Esteban-Medina, M. Peña-Chilet, K. Rian, S. Soliman, S. S. Aghamiri, B. L. Puniya, A. Naldi, T. Helikar, V. Singh, M. F. Fernández, V. Bermudez, E. Tsirvouli, A. Montagud, V. Noël, M. P. de Leon, D. Maier, A. Bauch, B. M. Gyori, J. A. Bachman, A. Luna, J. Pinero, L. I. Furlong, I. Balaur, A. Rougny, Y. Jarosz, R. W. Overall, R. Phair, L. Perfetto, L. Matthews, D. A. B. Rex, M. Orlic-Milacic, M. G. L. Cristobal, B. De Meulder, J. M. Ravel, B. Jassal, V. Satagopam, G. Wu, M. Golebiewski, P. Gawron, L. Calzone, J. S. Beckmann, C. T. Evelo, P. D’Eustachio, F. Schreiber, J. Saez-Rodriguez, J. Dopazo, M. Kuiper, A. Valencia, O. Wolkenhauer, H. Kitano, E. Barillot, C. Auffray, R. Balling, R. Schneider, . (2025). "A versatile and interoperable computational framework for the analysis and modeling of COVID-19 disease mechanisms." .
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Different B cell activation patterns in asymptomatic and symptomatic COVID-19 patients
Published in , 2025
Recommended citation: N. Pham, N. Talih, F. Ehrhart, C. T. Evelo, M. Kutmon. (2025). "Different B cell activation patterns in asymptomatic and symptomatic COVID-19 patients." .
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Glyoxalase-1 overexpression attenuates arterial wall stiffening in diabetic mice
Published in Cardiovascular Diabetology, 2025
Recommended citation: M. G. Pencheva, E. Berends, K. W. F. van der Laan, A. Giudici, P. Niessen, J. L. J. M. Scheijen, P. Vangrieken, P. Leenders, T. Delhaas, F. Caiment, M. Kutmon, F. M. Trujillo, K. Wouters, S. Foulquier, B. Spronck, K. D. Reesink, C. G. Schalkwijk. (2025). "Glyoxalase-1 overexpression attenuates arterial wall stiffening in diabetic mice." Cardiovascular Diabetology.
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Reproducible Exploration of Disease Maps with Galaxy Workflows and the MINERVA Platform
Published in , 2025
Recommended citation: H. Rasche, M. Hoch, J. Scheel, S. Hiltemann, M. Kutmon, C. T. Evelo, I. Cristoferi, M. van Baardwijk, A. Stubbs, M. Ostaszewski. (2025). "Reproducible Exploration of Disease Maps with Galaxy Workflows and the MINERVA Platform." .
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